Advanced Laparoscopic Pancreatic Surgery - From Training to Treating
Speaker: Atilla Nakeeb, MD
Indiana University Medical Center
Indianapolis, IN

Tomorrow’s Approach to Chronic Pancreatitis
Speaker: David B. Adams, MD
Medical University of South Carolina, Charleston, SC

Pancreas Case Studies/ Panel Discussion

Session II: LIVER TRANSPLANTATION
Moderator: Susan L. Orloff, MD
Professor, Department of Surgery, Oregon Health &
Science University, Portland VA Medical Center

Donation after Cardiac Death (DCD) Transplants - Optimizing the Value
Speaker: Scott R. Johnson, MD
Beth Israel Deaconess Medical Center, Boston, MA

Live Donor Liver Transplantation - Indications, Outcomes and
Controversies
Speaker: Amadeo Marcos, MD
University of Pittsburgh Medical Center, Pittsburgh, PA

Deceased Donor Liver Transplantation - Appropriate Use of Expanded Criteria Donors
Speaker: Speaker: Sandy Feng, MD
University of Michigan, Ann Arbor, Michigan

Hepatocellular Carcinoma - Values of Downstaging Prior
to Transplantation
Speaker: Will Chapman, MD
Washington University School of Medicine
St. Louis, MO

Liver Transplant Cases and Panel Discussion

Session III: State of the Art Lecture
Introduction: Mark P. Callery, MD
AHPBA President- Elect

“NOTES (tm) in HPB Disease”
Speaker: Ram Chuttani, MD
Director of Endoscopy Chief, Interventional Gastroenterology, Beth Israel Deaconess Medical Center , Harvard Medical School

Session IV: HEPATOBILIARY
Moderators: N. Joseph Espat, MD
Roger Williams Medical Center, Providence RI
David A. Iannitti, MD
Carolinas Medical Center, Charlotte, NC

Drug-Eluting Beads in the Treatment of Hepatic Malignancy
Speaker: Thomas Miner, MD
Brown University, Providence RI

Are Microwaves Ready for Primetime in Liver Ablation
Speaker: David M. Lloyd, MBBS, FRCS.
Leicester Royal Infirmary, Leicester, UK

Cyberknife Radio Therapy to Treat Primary and Metastatic Liver Tumors
Speaker: Robert M. Goldstein, MD
Baylor Regional Transplant Institute, Dallas, TX

Pre-transectional Radiofrequency Coagulation for Liver Resection
Speaker: Robert C. Martin, MD
University of Louisville, Louisville, KY

Remaining Obstacles In Laparoscopic Liver Surgery
Speaker: David A. Geller, MD
University of Pittsburgh, Pittsburgh, PA

Robotic Biliary Surgery
Speaker: John B. Martinie, MD
University of North Carolina, Chapel Hill, NC

President’s Plenary Session - Grand Salon A-E
The highest rated abstracts in each HPB discipline will be
presented during this session (Abstracts 1 - 8 )
Moderator: Bruce Schirmer

BRCA1 germline mutations as a cause of pancreatic cancer
Wigdan Al-sukhni, MD, Heidi Rothenmund, MS, Ayelet Borgida, MS, George Zogopoulos, MD, PhD, O’shea Anne Marie, MD, Steven Gallinger, MD, FRCP, University of Toronto, Toronto, ON,Canada; Samuel Lunenfeld Research Institute, Toronto, ON, Canada.
Discussant: Sean Mulvihill

Significance of AFPmRNA detected by real time PCR analysis after curative hepatectomy for hepatocellular carcinoma
Toshiya Kamiyama, MD, PhD, Kazuaki Nakanishi, MD, PhD, Hideki Yokoo, MD, PhD, Munenori Tahara, MD, PhD, Tsuyoshi Shimamura, MD, PhD, Hiroyuki Furukawa, MD, PhD, Michiaki Matsushita, MD, PhD, Satoru Todo, MD, PhD, Hokkaido University, Sapporo, Japan. Discussant: Henry Pitt

Intrahepatic Cholangiocarcinoma: Rising Incidence, Improved Survival And
Determinants Of Outcome After Resection
Itaru Endo, MD, Mithat Gonen, Qin Zhou, Kimberly Moore Dalal, MD, Michael D’angelica, MD, Ronald P. Dematteo, MD, Yuman Fong, MD, Lawrence Schwartz, MD, Nancy Kemeny, MD, Leslie H. Blumgart, MD, William R. Jarnagin, MD, Memorial Sloan-Kettering Cancer Center, New York, NY.
Discussant: Mike Choti

Clinical Response to Novel Dendritic Cell Based Vaccine Strategy in Pancreatic Cancer Predicted by Biologic Factors
Emmanuel E. Zervos, MD, James J. Mule, PhD, Nasreen Vohra, MD, Jennifer Cooper, MS, William Janssen, PhD, Domenico Coppola, MD, Alexander Rosemurgy, MD, East Carolina University, Greenville, NC; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; University of
South Florida, Tampa, FL; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. Discussant: Ron Dematteo

Liver Cell Adenoma: A Multicenter Analysis of Risk Factors for Rupture in 105 cases
Jeremiah Deneve, DO, Timothy M Pawlik, MD, MPH, Steven Cunningham, MD, Bryan M Clary, MD, Srinevas K Reddy, MD, Charles R. Scoggins, MD, Robert C. G. Martin II, MD, Charles A Staley III, MD, David Kooby, MD, Emory University, Atlanta, GA; Johns Hopkins, Baltimore, MD; Johns Hopkins University, Baltimore, MD; Duke University, Durham, NC; University of Louisville, Louisville, KY. Discussant: Scott Helton

Intention to treat survival following liver transplantation for hepatocellular
carcinoma within a donor service area
Kevin P Charpentier, MD, Yee Lee Cheah, MD, Jason Machan, PhD, Thomas Miner, MD, Paul Morrissey, MD, Anthony Monaco, MD, Rhode Island Hospital, Providence, RI.
Discussant: Wright Pinson

Does Screening for Hepatocellular Cancer Affect Outcome?
Chet Hammill, MD, Linda L Wong, MD, University of Hawaii, Honolulu, HI; Hawaii Medical Center - East, Honolulu, HI. Discussant: Milan Kinhabwala

Natural History and Surgical Treatment of Non-functional Pancreatic
Neuroendocrine Carcinoma: Population-based Analysis
Jan Franko, MD, PhD, Linwah W Yip, MD, Kenneth K Lee, MD, Alyssa M Krasinskas, MD, Herbert J Zeh III, MD, David L Bartlett, MD, Arthur J Moser, MD, University of Pittsburgh Medical Center, Pittsburgh, PA. Discussant: Ted Pappas

DVD 07 … U$ 50.00

Introduction of the President - Grand Salon A-E
Mark P. Callery, MD, AHPBA President-Elect
Beth Israel Deaconess Medical Center
Harvard Medical School, Boston, MA

Presidential Address
HPB Training During Residency
Bruce D. Schirmer, MD, President
University of Virginia
Charlottesville, VA

DVD 08 … U$ 50.00

Laparoscopic Hepatobiliary Surgery: Who, What, When?
AHPBA/SAGES Symposium
Moderators: David Ianitti and Will Chapman

Laparoscopic Liver Resection
The Case For: Joe Buell
The Case Against: Alan Hemming

Laparoscopic Donor Hepatectomy
The Case For: Alan Koffron
The Case Against: Paul Greig

Laparoscopic Pancreatectomy
The Case For: Michele Gagner
The Case Against: Mike Zenilman

Discussion: Is there a consensus?
What are the indications for laparoscopic liver and pancreatic resection? This session will feature a balanced presentation of the advantages and potential
problems related to minimally invasive hepatic and pancreatic surgery. The available data will be presented and the indications for minimally invasive
procedures will be debated.

State of the Art Lecture - Grand Salon E
Pancreatic Resection for Ductal Adenocarcinoma: Technical Considerations and Current State of the Art
Introduction: Bruce Schirmer
Speaker: Masao Tanaka Professor and Chairman
Department of Surgery and Oncology Graduate School of Medical Services
Kyushu University, Fukuoka, Japan

President's Invited Speaker - Current Topics in Health Care
Introduction: Bruce Schirmer

Speaker: R. Scott Jones
Professor and Chairman of Surgery Emeritus, Department of Surgery, University of Virginia, Former President, American College of Surgeons, American Surgical Association, Southern Surgical Association, ans Society for Surgery of the Alimentary Tract Past Head, Division of Research and Optimal Patient Care, American College of Surgeons

SPECIAL DEBATE 1
Management of Pancreatic Cystic Neoplasms
Moderator: Mark Callery Radiology: Larry Schwartz
Debate: Murray Brennan vs. Keith Lillemoe

Debate: Murray Brennan vs. Keith Lillemoe
‘The risk of cancer is low for small lesions - close imaging follow-up and selective resection is the best approach Murray Brennan

‘The cancer risk is high for all lesions - an aggressive policy of resection is therefore warranted’ Keith Lillemoe

Rebuttal/Discussion
The management of pancreatic cystic neoplasms continues to evolve, and
areas of controversy remain. This session will feature a presentation of the
relevant imaging characteristics of these lesions, followed by a debate of
management approaches for this difficult clinical problem.

SPECIAL DEBATE 2
Benign Liver Tumors: Changing Management Paradigm?
Moderator: Nicolas Vauthey Radiology: Vamsidha Narra
Debate: David Geller vs. Yuman Fong

‘Close imaging follow-up is the best strategy in most patients with suspected benign tumors’ Yuman Fong

‘Laparoscopic resection should be used more liberally in the management of suspected benign tumors?’ David Geller

Rebuttal/Discussion
Benign liver tumors are common and most require no intervention. However,diagnostic uncertainty remains a major source of anxiety for both patient and surgeon. In this regard, differentiating between hepatic adenoma and FNH and is a frequent and particularly difficult problem. This debate will be centered around the following question: Should hepatic resection be used more often in the diagnostic algorithm of patients with suspected benign liver tumors, particularly as minimally invasive hepatic resection techniques improve?

Angiotensin II induces Vascular Endothelial Growth
Factor in Pancreatic Cancer Cells
Hwyda A. Arafat, MD, PhD, Galina Chipitsyna, PhD, Qioake Gong, MD, Rathai Anandanadesan, MD, Charles J. Yeo, MD, Thomas Jefferson Univesity, Philadelphia, PA. Discussant: Courtney Scaife

Hepatic Interferon Regulatory Factor - 1 Expression During Liver Ischemia Reperfusion Injury is TLR-4 Dependent
Jon S Cardinal, MD, Rajeev Dhupar, MD, Geetha Jeyabalan, MD, Allan Tsung, MD, David Geller, MD, University of Pittsburgh Medical Center, Pittsburgh, PA. Discussant: Kenneth Chavin

MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of Survival
Mary Dillhoff, MD, Wendy L Frankel, MD, James Liu, MD, Mark Bloomston, MD, Ohio State University, Columbus, OH. Discussant: Doug Tyler

Differential expression of pro-inflammatory cytokines and EMC remodeling enzymes by ED2dim hepatic macrophages versus ED2high Kupffer cells in rat livers
Gordon D Wu, MD, Yao He, MD, PhD, Andrew S Klein, MD, Cedars-Sinai Medical Center, Los Angeles, CA. Discussant: Rob Glasgow

TLR4 signaling causes increased damage to steatotic livers after ischemia/reperfusion injury
Justin D Ellett, B.Sc., Zachary P Evans, PhD, Michael G Schmidt, PhD, Kenneth D Chavin, MD, PhD, Medical University of South Carolina, Charleston, SC. Discussant: David Geller

Exploration of anti-VEGF Mechanisms in Experimental Pancreatic Cancer
Niranjan Awasthi, PhD, Margaret Schwarz, MD, Srivani Konduri, PhD, Varun Verma, MS, Clint Capiello, MS, Roderich E Schwarz, MD, UT Southwestern Medical Center, Dallas, TX; UMDNJ - Robert Wood Johnson Medical School, New Brunswick, NJ. Discussant: Brendan Visser

Focal adhesion kinase (FAK) regulates the metastatic phenotype of gastrointestinal carcinoid cancer cells through the Raf-1 signaling pathway
Li Ning, MD, Muthusamy Kunnimalaiyaan, PhD, Herbert Chen, MD, University of Wisconsin, Madison, WI. Discussant: Carlos Corvera

Combined TRAIL and HSP70-inhibition therapy induces apoptosis synergistically in human pancreatic cancer cells
Daniel Borja-cacho, MD, Pawel Zwolak, MD, Vikas Dudeja, MD, Selwyn M Vickers, MD, Ashok K Saluja, PhD, University of Minnesota, Minneapolis, MN. Discussant: David Linehan

Suppression of Pancreatic Carcinoid Tumor Cell Growth and Neuroendocrine Hormone Production by Akt-1 Inhibition
Susan C Pitt, MD, Herbert Chen, MD, Muthusamy Kunnimalaiyaan, PhD, Endocrine Surgery Research Laboratories, University of Wisconsin, Madison, WI. Discussant: Mark Callery

A Comparison of Pancreaticoduodenectomy and Duodenal Sparing Head Resection for the Treatment of Chronic Pancreatitis
Rebecca J Mcclaine, MD, Andrew M Lowy, MD, Andres Gelrud, MD, Nathan Schmulewitz, MD, Shailendra Chauhan, MD, Laura E James, MS, Jeffrey J Sussman, MD, Jeffrey B Matthews, MD, Syed A Ahmad, MD, University of Cincinnati, Cincinnati, OH; University of California, San Diego, La Jolla, CA; University of Chicago, Chicago, IL. Discussant: Thom Schnelldorfer

Fungal Infection In Necrotizing Pancreatitis Causes A Dramatic Rise In Morbidity And Mortality
Yuriy Zhukov, Thomas J Howard, MD, Lee Mchenry, MD, Evan L Fogel, MD, Attila Nakeeb, MD, Henry A Pitt, MD, Keith D Lillemoe, MD, Christian M Schmidt, MD, Nicholas J. Zyromski, MD, Indiana University School of Medicine, Department of Surgery, Indianapolis, IN. Discussant: Taylor Riall

Determining Pattern of Recurrence following Pancreaticoduodenectomy: Effect of Lymph Node Ratio and Number of Positive Nodes
Bolanle Asiyanbola, MD, Joseph Herman, MD, Ana Gleisner, MD, Michael Choti, MD, Christopher Wolfgang, MD, PhD, Richard Schulick, MD, John Cameron, MD, Timothy M Pawlik, MD, Johns Hopkins, Baltimore, MD. Discussant: AJ Moser

The Latent Presentation of Pancreatic Fistulae
Wande Pratt, Mark Callery, MD, Charles Vollmer, MD, Beth Israel Deaconess Medical Center,Boston, MA.
Discussant: John Christien

Survival After Pancreaticoduodenectomy Is Not Improved By Extending Resections To Achieve Negative Margins
Jonathan M Hernandez, MD, Desiree Villadolid, MPH, Paul Toomey, B.Sc., John Mullinax, MD, C Whalen Clark, MD, Lorraine Tomlinson, None, Steven Goldin, MD, PhD, Alexander Rosemurgy,MD, University of South Florida College of Medicine Department of Surgery, Tampa, FL. Discussant: Chuck Vollmer

Presence of Symptoms, Tumor Size, and Imaging Characteristics do not Reliably Predict Malignancy in Mucinous Cystic Neoplasms of the Pancreas
Jayme B. Stokes, MD, Edward B. Stelow, MD, Marc Sarti, MD, Eduard E. De Lange, MD, Reid B. Adams, MD, Todd W. Bauer, MD, University of Virginia, Charlottesville, VA. Discussant: Julie Stein

Cyberknife Radiosurgery for Pancreatic Cancer
Anand Mahadevan, Michael Goldstein, Sanjay Jain, Mark Callery, Charles Vollmer, BethIsrael Deaconess Medical center, Boston, MA.
Discussant: Gary Rosato

Antibacterial Prophylaxis Does Prevent Death From Acute Necrotising Pancreatitis, But Not By Preventing Infection Of Pancreatic Necrosis
Eduardo A Villatoro, MD, Mubashir Mulla, MD, Richard I Hall, MD, MBBS, Michael Larvin, MD, MBBS, University of Nottingham at Derby, Derby, United Kingdom; Derby Hospitals NHS Foundation Trust, Derby, United Kingdom.
Discussant: Nick Zyromski

A Genetic Expression Profile of Chemoresistant Pancreatic Cancer
Anthony Razzak, B.Sc., Abdul Saeid, MD, Jose Trevino, MD, Justin Hering, MD, Joseph Espat, MD, Roger Williams Cancer Center, Providence, RI. Discussant: Doug Tyler

Imaging Primary Malignancies of the Liver Vamsidha Narra
Imaging the IPMN Spectrum Lawrence Schwartz
Molecular Imaging in Hepatobiliary Disease Timothy Akhurst

Monitoring Response to Local Therapies David Grand
Improvements in imaging continue at a rapid rate and profoundly influence the practice of HPB surgery.

DVD 19 … U$ … 50.00

Surgical Specialization and Operative Mortality in HPB Surgery
Nicholas Csikesz, B.Sc., Shimul A Shah, MD, University of Massachusetts, Worcester, MA. Discussant: Marwan Abouljoud

A Simplified Utilitarian Bile Duct Injury Classification: Based on Mortality,Financial, and Re-stricture Data
Ravi Nagubandi, MD, Michael Marvin, MD, Steve Rudich, MD, Ravindra Kadiyala, MD, Amit Tevar, MD, Michael Nussbaum, MD, Andreas Gelrud, MD, Jeff Mathews, MD, Tariq Shaqoor, MD, Joseph Buell, MD, Jewish Hospital, University of Louisville, Louisville, KY; University of Cincinnati, Discussant: Bill Hawkins

Carcinoma of the Extrahepatic Bile Ducts: A Comparison of Proximal and Distal Lesions
Peter J Allen, MD, David Klimstra, MD, Michael D’angelica, MD, Ronald Dematteo, MD, Yuman Fong, MD, Leslie H Blumgart, MD, Murray F Brennan, MD, William R Jarnagin, MD, Memorial Sloan-Kettering Cancer Center, New York, NY. Discussant: Tim Pawlik

“Sideways”: Results Of Repair Of Biliary Injuries Using A Policy Of Side-To-Side Hepatico-Jejunostomy (Hj)
Emily R Winslow, MD, Elizabeth A Fialkowski, MD, David C Linehan, MD, William G Hawkins, MD, Steven M Strasberg, MD, Washington University School of Medicine Discussant: Mike D’Angelica

Bile duct injuries associated with laparoscopic cholecystectomy: timing of repair determines long term outcomes
Simon C Chow, Ajay K Sahajpal, Elijah Dixon, Paul D Greig, David R Grant, Bryce R Taylor, Mark Cattral, Steve Gallinger, Alice C Wei, Division of General Surgery, University of Toronto, Toronto, ON, Canada; Mayo Clinic, Rochester, MN; University of Calgary, Calgary, AB, Canada; Toronto General Hospital, University Health Network, Toronto, ON, Canada; Mount Sinai Hospital,
Discussant: David Koo

The Influence of Body Mass Index on the Incidence and Severity of Biliary Infections
Lygia Stewart, MD, J Mcleod Griffiss, MD, Gary A Jarvis, PhD, Lawrence W Way, MD, UCSF /SF VAMC, San Francisco, CA; UCSF, San Francisco, CA.
Discussant: Peter Lodge

Impact of tumor extent and lymph node involvement on survival in gallbladder adenocarcinoma
Victor Zaydfudim, MD, Irene D. Feurer, PhD, C. Wright Pinson, MD, MBA, Vanderbilt University Medical Center, Nashville, TN.
Discussant: Bill Jarnagin

Timing of Referral Impacts Surgical Outcomes in Patients Undergoing Repair of Bile Duct Injuries
Craig P. Fischer, MD, MPH, Bridget N. Fahy, MD, Thomas A. Aloia, MD, Barbara L. Bass, MD, Weill Medical College of Cornell University, Houston, TX.
Discussant: Alex Rosemurgy

The Obstructed Pancreato-Biliary Limb: Presentation, Management and Outcomes
David Odell, MD, Wande Pratt, Mark Callery, MD, Charles Vollmer, MD, Beth Israel Deaconess Medical Center, Boston, MA.
Discussant: Nipun Merchant

INVITED VIDEO SESSION 2: LIVER
Moderator: Peter Lodge

Partial Hepatectomy with Portal Vein Reconstruction - Peter Lodge
Principles of Resection for Hilar Cholangiocarcinoma - Jonathan Koea
Living Donor Hepatectomy – Amadeo Marcos
Laparoscopic Hemi-hepatectomy with Pedicle Ligation - David Linehan

Competitive Video Session 1 and 2
Competitive Video Session 1: Pancreas Abstracts 123 - 128a
Moderators: D. Rohan Jeyarajah & Richard Schulick

Laparoscopic Spleen-Preserving Total Pancreatectomy For Multifocal Ipmn
Michael L Kendrick, MD, Mayo Clinic, Rochester, MN.

Laparoscopic Distal Pancreatectomy with Splenic Preservation
Richard A Mackey, MD, R. Matthew Walsh, MD, St. Joseph Medical Center, Towson, MD; Cleveland Clinic, Cleveland, OH.

Central Pancreatectomy with Pancreaticogastrostomy for Mucinous Cystadenoma of the Pancreatic Neck
David A Kooby, MD, Emory University, Atlanta, GA.

Duodenal Gastro Intestinal Stromal Tumor. Laparoscopic Treatment
Sergio E Bustos, MD, Jorge Eduardo Nefa, MD, Pablo Esteban Omelanczuk, MD, Italian Hospital of Mendoza, Mendoza, Argentina.

Pancreatogenous Adult Hyperinsulinemic Hypoglucemia Syndrome
Juan Pekolj, MD, Diego Lucas Fernández, MD, Juan Antonio Salceda, MD, Mariano Bregante, MD, Eduardo De Santibanñes, MD, Hospital Italiano Buenos Aires, Buenos Aires, Argentina.

Hepato-Pancreato-Biliary Surgery: Effect of Surgical Casemix on Peri-Operative Mortality
Hari Nathan, MD, Michael Choti, MD, Richard D Schulick, MD, Timothy M Pawlik, MD, Johns Hopkins, Baltimore, MD. Discussant: Rohan Jeyarajah

Accurate radiological diagnosis of microinvasion of portal vein in hepatocellular carcinoma by distortion of the corona enhancement, tumoral arterioportal shunt and perilesional hyperintense rim
Ryohei Miyata, MD, Akihiro Tanimoto, MD, Go Wakabayashi, MD, Masaki Kitajima, MD, Tokyo Dental College, Chiba, Japan; Keio University, Shinjuku Tokyo, Japan.
Discussant: Sean Cleary

Societal reintegration and Economic implications following orthotopic liver transplant
Michele Molinari, MD, Amy Gillis, MD, Mark Joseph Walsh, MD, Dalhousie University, Halifax, NS, Canada. Discussant: Shawn Pelletier

Outcomes Associated with Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemotherapy for Colorectal Cancer Patients with Peritoneal Carcinomatosis and Hepatic Metastases
Oliver A Varban, MD, Edward A. Levine, MD, John H. Stewart, MD, Thomas Mccoy, MS, Perry Shen, MD, Wake Forest University Medical Center, Winston-salem, NC. Discussant: Jim Pingpank

Outcomes in Pancreatic Resection are Negatively Influenced by Preoperative Hospitalization
Wande Pratt, Charles Vollmer, MD, Mark Callery, MD, Beth Israel Deaconess Medical Center, Boston, MA.
Discussant: John Martini

New Abdominal Intraoperative Ultrasound Phantom Replacing the Animal Lab to Teach Surgeons
Leo Villegas, MD, Junji Machi, MD, Maurice Arregui, MD, Takayuki Ohara, Toshi Takayama, Hidenobu Katayama, University of Missouri Kansas City, Kansas City, MO; n/a, Honolulu, HI; n/a, Indianapolis, IN; Kyoto Kagaku, Torrance, CA.
Discussant: Bill Jarnagin